Peptides and Vaccines


As you already know, peptides are nothing but proteins, which are biological mechanisms that act as enzymes, mediators of cell signals, receptors and structural cell components. A lot of research has been going on in regards to how peptides can be used to improve drug delivery across various targets in the body. There is also extensive research about peptides and vaccines and here is brief look into some recent developments.

Anti-tumor peptides

There are quite a number of reasons for the occurrence of tumors. But ultimately, their occurrence is related to the regulation of various expressions in the oncogenes. Different tumors need different enzymes to act as regulatory factors and it is at this state when peptides can be exploited. They can be used in the active sites to stop the spread of tumors since tumors are normally smaller than the regulatory factors.


A classic example is in the case of rotigaptide, which is aimed at treating cardiac arrhythmias. Though still under clinical trials, it has been discovered that tumor and tumor related gene regulatory factors are now the hot spots for finding anti-cancer drugs by targeting and screening certain specific binding peptides. Researchers have come to the conclusion that small peptides have the ability to stop the growth of cancer cells, including colorectal, stomach and lung cancer. These have provided avenues for more research about the use of peptides as a treatment against cancer.

Anti-viral polypeptide

Viral infections normally happen through several stages. These include adsorption, penetration, nucleic acid replication, uncoating, transcription, translation and packaging. If any of these processes are prevented, then it could be possible to stop the replication of the virus. Peptides are currently being studied and screened with polypeptides binding on the host cell receptors to interfere with the process of viral replication. As such, peptides are now being considered as anti-viral therapy.